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主管单位 工业和信息化部 主办单位 哈尔滨工业大学 主编 任南琪 国际刊号ISSN 1672-5565 国内刊号CN 23-1513/Q

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引用本文:苏怡,刘旭东,仲伟麒,李鑫,宋会荣,白晶,董锐,郑晓华.对一起诺如病毒感染疫情的流行病学调查分析[J].生物信息学,2022,20(2):136-140.
SU Yi,LIU Xudong,ZHONG Weiqi,LI Xin,SONG Huirong,BAI Jing,DONG Rui,ZHENG Xiaohua.Epidemiological survey and analysis of a norovirus infection epidemic[J].Chinese Journal of Bioinformatics,2022,20(2):136-140.
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对一起诺如病毒感染疫情的流行病学调查分析
苏怡1,刘旭东2,仲伟麒1,李鑫1,宋会荣2,白晶1,董锐1,郑晓华1
(1.黑龙江省疾病预防控制中心,哈尔滨 150030;2.黑龙江省哈尔滨市道里区疾病预防控制中心,哈尔滨 150010)
摘要:
分析一起发生在某幼儿园的诺如病毒暴发疫情,为预防预警此类事件提供科学参考依据。采用现场流行病学调查的方法描述疫情的发生过程、三间分布、临床特征、确认检验。采集相关人员肛拭子标本、可疑食物、剩余食品、餐具样品、饮用水样本等,开展有效的实验室检测。在搜索的34例病例中,临床诊断病例为29例,实验室确诊病例为 5例,隐性感染者16例,罹患率为16.59 %,无重症和死亡病例。病例分布在各楼层的5个班级,年龄2-5岁之间。症状主要为呕吐(100%)、腹泻(23.52%)、恶心(55.88%)、腹痛(58.82%)、发热(67.65%)。实验室检验结果为诺如病毒GII型和GI型、GII型混合,常见肠道致病菌均为阴性。依据《诺如病毒感染暴发调查和预防控制技术指南(2015版)》,结合流行病学调查资料、病例临床表现及实验室检测结果,研判本起事件为人员交叉感染诺如病毒引起的暴发性疫情。加强对幼儿园全方位管理、开展相关健康教育宣传和防控培训,对有效预防和减少类似疫情的发生尤为重要。
关键词:  诺如病毒  感染性腹泻  流行病学调查  暴发疫情。
DOI:10.12113/202110012
分类号:R515.1
文献标识码:A
基金项目:
Epidemiological survey and analysis of a norovirus infection epidemic
SU Yi1,LIU Xudong 2,ZHONG Weiqi1,LI Xin1,SONG Huirong2,BAI Jing1,DONG Rui 1,ZHENG Xiaohua1
(1.Heilongjiang Provincial Center for Disease Control and Prevention,Harbin 150030,China; 2. The Center for Disease Control and Prevention in Daoli District of Harbin,Harbin 150010,China)
Abstract:
A norovirus outbreak in a kindergarten was analyzed to provide scientific reference for the prevention and early warning of such incidents. On-site epidemiological investigation was applied to describe the outbreak process, three distribution, clinical characteristics, and confirmation tests. Anal swab samples, suspicious food, surplus food, tableware samples, and drinking water samples of relevant personnel were collected to carry out laboratory tests.Of 34 cases searched, 29 were clinically diagnosed, 5 were laboratory confirmed, and 16 were recessive infections.The development rate was 16.59%, and there were no severe or dead cases. Cases were distributed in five classes of different floors, and the age range was between 2 and 5 years old. The symptoms were mainly vomiting (100%), diarrhoea (23.52%), nausea (55.88%), abdominal pain (58.82%), and fever (67.65%). Laboratory tests showed a mixture of norovirus GII and GI and GII, and all common intestinal pathogenic bacteria were negative.According to the “Guidelines on Outbreak Investigation, Prevention and Control of Norovirus Infection (2015 edition)”, through analysis of the epidemiological investigation data, case clinical manifestations, and laboratory test results, the outbreak was caused by the cross-infection of norovirus. Strengthening the all-round management of kindergartens and carrying out relevant health education and prevention and control training are particularly important to effectively prevent and reduce the occurrence of similar epidemics.
Key words:  Norovirus  Infectious diarrhea  Epidemiological investigations  Outbreaks

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