| 打分矩阵方法在β-发夹模体识别中的应用 |
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| 引用本文： | 姜雪,胡秀珍.打分矩阵方法在β-发夹模体识别中的应用[J].生物信息学,2008,6(4):156-158. |
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| 作者姓名： | 姜雪 胡秀珍 |
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| 作者单位： | 1. 内蒙古工业大学理学院,呼和浩特,010051;沈阳工业大学辽阳校区基础部,辽阳,111003
2. 内蒙古工业大学理学院,呼和浩特,010051 |
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| 摘 要： | 用打分矩阵的五种算法，从蛋白质的氨基酸序列出发，以氨基酸为参数，分别对3088个同源性小于40％的蛋白质和2878个同源性小于33％的蛋白质的β-发夹模体片断进行了识别。利用self—consistency和10—fold cross—validation两种方法对五种算法进行检验，结果表明，Claverie（1996）算法相对较好，对3088个蛋白质的平均识别精度达到了77．7％和76．1％。
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| 关 键 词： | β-发夹模体 位置打分矩阵 位置打分函数 |
The Recognition of β-Hairpin Motifs in the Protein: Approached by Scoring Matrix |
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| JIANG Xue,HU Xiu-zhen.The Recognition of β-Hairpin Motifs in the Protein: Approached by Scoring Matrix[J].China Journal of Bioinformation,2008,6(4):156-158. |
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| Authors: | JIANG Xue HU Xiu-zhen |
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| Affiliation: | JIANG Xue, HU Xiu - zhen ( 1. College of Sciences, Inner Mongolia University of Technology, Hohhot 010051, P. R. C; 2 . department of basic , Shen Yang University of Technology liaoyang campus , Liaoyang 111003 , P. R. C) |
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| Abstract: | Based on amino acid sequences of the 3088 protein chains with identity 〈 40% and 2878 protein chains with identity 〈 33%, respectively, by using of the 5 kinds scoring matrix for predicting a - hairpin motif is proposed with parameter by amino acid in the self- consistency and 10 - fold cross - validation. Predictive results shown （1996） algorithm is significantly better than others, the overall predicted accuracies are 77.7% and 76.1% for 3088 proteins respectively. |
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| Keywords: | β- hairpin motif position scoring matrix scoring function |
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