| 摘要: |
| 结构域是蛋白质序列中具有独特功能的区域,这些区域影响着蛋白质的功能,因此研究结构域的特征对于了解蛋白质功能很有帮助。构建革兰氏阳性菌蛋白质4个亚细胞位置数据集,对该数据集中的蛋白质进行结构域的搜索和功能分析,找到了革兰氏阳性菌的细胞壁、细胞质、细胞膜和细胞外四个蛋白质区域的结构域。分析这四个位置结构域的功能并在PDBsum 数据库中找到了这些结构域的二级结构和三级结构图,利用这些特征信息可以更深入的了解革兰氏阳性菌蛋白质的结构和功能。 |
| 关键词: 革兰氏阳性菌 结构域 特征 |
| DOI：10.12113/201909002 |
| 分类号:Q61 |
| 文献标识码:A |
| 基金项目:国家自然科学基金项目(No.31360206); 内蒙古自治区自然科学基金项目(No.2019MS03015). |
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| Analysis of domain feature of gram-positive bacterial protein |
|
GAO Xiaowei, LI Fengmin
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(College of Science, Inner Mongolia Agriculture University, Hohhot 010018, China)
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| Abstract: |
| Domain is the region with unique function in protein sequence, which influences the function of protein. Therefore, research on the characteristics of domain is helpful to understand the function of protein. In this paper, the datasets of 700 proteins from 4 sites of Gram-positive bacteria were reconstructed. Through searching and functional analysis of the domains of the proteins in the dataset, the domains of the cell wall, cytoplasm, membrane, and extracellular areas of Gram-positive bacteria were found. Functions of these positional domains were analyzed, and the secondary and tertiary structures of these domains were found in the PDBsum database. The characteristic information can be used to further understand the structure and function of Gram-positive bacterial protein. |
| Key words: Gram-positive bacteria Domain Characteristics |
